【简介】

理学博士，杭州师范大学材料与化学化工学院副教授。长期从事人造折叠体，人工跨膜通道，医用纳米材料，仿生材料等方向的研究。目前主持国家自然科学基金青年项目1项，在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Mater., Adv. Funct. Mater., Nano Lett., 等国际著名期刊发表SCI论文30余篇。

【研究方向】

人造折叠体，人工跨膜通道，医用纳米材料，仿生材料等

【教育和工作经历】

2023年-至今：杭州师范大学，材料与化学化工学院，副教授

2020年-2022年：中南大学-杭州师范大学，联合培养博士后

2014年-2019年：吉林大学，化学学院，高分子化学与物理，理学博士

【科研项目】

1. 国家自然科学基金青年项目，基于喹啉螺旋构筑单分子人工质子跨膜通道，30万，主持，2022.01–2024.12。

2. 国家自然科学基金国际(地区)合作与交流项目，基于竹环构筑选择性氯离子转运体和通道，200万，参与，2022.01-2024.12。

【代表性论著】

1. Yueyue Lu, Yuxin Wu, Canhong Zhu, Tianlong Zhang, Yanting Wu, Lulu Xi, Xianze Huang, Tengfei Yan,* and Junqiu Liu*. Light-Sensitive Ion Channel Delivery System for Ion-Interference Tumor Therapy. JACS Au, 2025, 5, 4439−4448.

2. Cong Li, Yaqi Wu, Sheng Bao, Hui Li, Zhengwei Xu, Jing Yan, Xiaoxuan Yu, Lei He, Tianlong Zhang, Wang Liu, Shida Hou, Yang Zhang, Jiayun Xu, Tengfei Yan,* Tingting Wang,* Yi Yan,* and Junqiu Liu*. Photo-Switchable Supramolecular Interactions Regulate K⁺ Transmembrane Transport and Cancer Cell Apoptosis. J. Am. Chem. Soc. 2025, 147, 14139−14153

3. Yaqi Wu, Qiangqiang Xu, Yaoxuan Chen, Cong Li, Yanliang Wu, Xiaoxuan Yu, Hui Li, Zhengwei Xu, Jiayun Xu, Zhigang Ni, Yan Ge, Tengfei Yan,* Zhenhui Qi,* and Junqiu Liu*. Mechanosensitive and pH-Gated Butterfly-Shaped Artificial Ion Channel for High-Selective K⁺ Transport and Cancer Cell Apoptosis. Adv. Mater. 2025, 2416852.

4. Tengfei Yan, Junqiu Liu* Transmembrane Ion Channels: From Natural to Artificial Systems. Angew. Chem. Int. Ed. 2024, e202416200

5. Cong Li, Yaqi Wu, Yihang Zhu, Jing Yan, Shengda Liu, Jiayun Xu, Shixin Fa, Tengfei Yan,* Dingcheng Zhu,* Yi Yan,* and Junqiu Liu*. Molecular Motor-Driven Light-Controlled Logic-Gated K⁺ Channel for Cancer Cell Apoptosis. Adv. Mater. 2024, 2312352.

6. Yaqi Wu, Cong Li, Yanliang Wu, Jiayun Xu, Zhigang Ni, Ofer Reany, Tengfei Yan,* Dingcheng Zhu,* and Junqiu Liu*. A Reversible Light-Driven Biomimetic K⁺/Na⁺-Exchanger Controls Cancer Cell Apoptosis. Adv. Funct. Mater. 2024, 2400432.

7. Tengfei Yan, Shengda Liu, Cong Li, Jiayun Xu, Shuangjiang Yu, Tingting Wang,* Hongcheng Sun,* and Junqiu Liu*. Flexible Single-Chain Heteropolymer-Derived Transmembrane Ion Channels with High K⁺ Selectivity and Tunable pH-Gated Characteristics. Angew. Chem. Int. Ed., 2022, 61, e202210214.

8. Dongya Bai^#, Tengfei Yan^#, Shi Wang, Yanbo Wang, Jiya Fu, Xiaomin Fang, Junyan Zhu,* and Junqiu Liu*. Reversible Ligand-Gated Ion Channel via Interconversion between Hollow Single Helix and Intertwined Double Helix. Angew. Chem. Int. Ed., 2020, 59, 13602−13607.

9. Tengfei Yan, Shengda Liu, Jiayun Xu, Hongcheng Sun*, Shuangjiang Yu*, and Junqiu Liu*. Unimolecular Helix-Based Transmembrane Nanochannel with a Smallest Luminal Cavity of 1 Å Expressing High Proton Selectivity and Transport Activity. Nano Lett., 2021, 21, 10462−10468.

【电子邮箱】tengfeiyan@163.com